Proudly Serving Canadians Since 2012Prednisone
Classification: Synthetic glucocorticoid
Estrogenic Activity None
Progestational Activity None
Water Retention: None
Aromatization: None
Hepatotoxicity: Low
Half-life: 2-3 hours
Recommended Dosage: 5- 40 mg/day
Prednisone General Info
Prednisone is a synthetic glucocorticoid medication that was developed in the 1950s and became commercially available in 1955.
Prednisone is FDA-approved and included in the World Health Organization's List of Essential Medicines. The WHO list contains only the most effective and safe medications used in clinical medicine.
Glucocorticoids General Info
Glucocorticoids are a crucial part of the immune system feedback mechanism. Glucocorticoids are responsible for reducing some aspects of the hyperactive immune system, such as inflammation.
Glucocorticoids are vital for the support and proper functioning of the cardiovascular and immune systems. Synthetic glucocorticoids are widely used in clinical medicine as replacement therapy in cases of glucocorticoid deficiency or as a suppressant of the hyperactive immune system.
Inflammation General Info
Inflammation is a critical protective response to harmful stimuli or bacteria that could lead to progressive tissue destruction. The inflammation process involves immune cells, molecular mediators, and blood vessels. However, chronic and severe inflammation as a hyperactive immune system response could lead to prolonged tissue destruction with slower healing timing.
Prednisone Main Usage
Prednisone is a very effective medication used as a treatment for:
severe inflammation
rheumatologic diseases (a condition that causes pain and affects joints and connective tissues)
osteoarthritis
mixed connective tissue disease
acute lymphocytic leukemia
adrenal insufficiency
Skin rash and allergic disorders
cluster headaches (severe pain on one side of the head, typically around the eye)
Prednisone Administration
Please start Prednisone therapy with a 5mg/day dosage. If 5mg/day dosage does not provide desired results, please increase the dosage to 10mg/day. Recommended clinical dosage range is between 5mg-40 mg/day. Please note that the best time to take Prednisone is in the morning before 9 AM. To avoid or decrease potential gastrointestinal discomfort, please take Prednisone with food.
Resistance to Prednisone
Please note that due to a genetic predisposition, some people are unresponsive to Prednisone and other Glucocorticoids.
Prednisone Effectiveness
Prednisone is an effective medication used for multiple health conditions.
Prednisone users' ratings on Prednisone effectiveness for certain medical conditions.
(10 being the highest rating)
Inflammation 9 out of 10
Rheumatoid Arthritis 8.1 out of 10
Osteoarthritis 9.5 out of 10
Mixed connective tissue disease 8.7 out of 10
Acute lymphocytic leukemia 10 out of 10
Skin rash 6.6 out of 10
Cluster headaches 8.9 out of 10
Acute Crohn's Disease 3.0 out of 10
Allergic Rhinitis 2 out of 10
Multiple Sclerosis 1.0 out of 10
Prednisone Possible Side Effects
Prednisone is a very potent compound. The overdose and the extended usage (more than three weeks) could lead to side effects such as diarrhea, abdominal pain, increased thirst, increased appetite, acne, fatigue, and weakness, increased blood sugar (users with diabetes), blurred vision, insomnia.
Dosage and packing: 5mg/100tabs