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Cobalt Pramipexole 1mg/10tabs (Prolactin Inhibitor)

Brand: Cobalt, Canada

Substance: Pramipexole

Dosage and packing: 1 mg/tab (10 tabs)

$40.00

Availability: In stock

Brand: Cobalt, Canada

Substance: Pramipexole

Dosage and packing: 1mg per tab

Size: 10 tabs

Description

Details

Pramipexole General Description

Pramipexole is a dopamine antagonist that is part of the same class of drugs as Cabergoline. The main use of the drug in medical practice is the treatment of Parkinson's disease. In addition to treating this disease, Pramipexole is also used to eliminate problems with the lower extremities; in some situations, the drug helps treat bipolar depression. The drug is often found under the trade names Mirapexin, Sifrol or Mirapex.
Pramipexole has dopamine in its composition, which interacts directly with the prolactin hormone. When the concentration of dopamine in the body is increased, the amount of prolactin gradually decreases. This effect is achieved by direct exposure of dopamine to the D3 receptor. Such a process greatly affects the neurological system.
Due to the influence of Pramipexole on the D3 receptor, the sexual vigor of a person is increased. Prolactin has an effect on the refractory period, meaning the time required for recovery after sexual contact and finding additional resources for more sexual intercourse. By reducing the concentration of prolactin and increasing dopamine levels, Pramipexole significantly reduces this period of time and allows users to engage in more intense sexual activity.
Pramipexole gained great popularity in sports. It is often used by athletes during the usage of trenbolones and nandrolones to suppress the concentration of prolactin, which can lead to negative side effects in the form of gynecomastia, flaccid erection and other symptoms. Pramipexole is an excellent alternative to Cabergoline, Dostinex, Agalates and other drugs.

Pramipexole Benefits

Pramipexole is often used in medicine to treat Parkinson's disease, but athletes also commonly use the drug. Athletes appreciate the dopamine antagonist for its ability to combat prolactin gynecomastia that occurs during the usage of trenbolones and nandrolones, as well as for the ability to improve sexual function, which can become quite suppressed due to the use of anabolic substances.
The drug’s active agent is completely absorbed in the digestive tract. The highest concentration of Pramipexole in the blood is reached 2 hours after administration. Food extends the period of reaching maximal concentration for an hour, but it does not affect the absorption of the substance. The total bioavailability of the dopamine antagonist is 90%; it is accumulated mainly in red blood cells. Within 2 days after the start of administration, a stable concentration of the drug is achieved. Pramipexole is affected by metabolic processes in insignificant capacity. The active component is excreted from the body almost completely by the kidneys, which is about 90% of the consumed dose.
When an increase in prolactin concentration occurs in the body, an increase in estrogen concentration is observed at the same time, which leads to gynecomastia. Athletes with a genetic predisposition are particularly prone to this effect. Not all men suffer from symptoms of gynecomastia when using anabolic-androgenic steroids if proper dosages are adhered to.
High prolactin levels have a negative effect on human sexual function, which significantly reduces the likelihood of a normal erection occurring in men. Such adverse reactions are often manifested during the use of nandrolones. It is worth noting that sexual impotence during steroid cycles manifests individually – some athletes may experience opposite symptoms in the form of stimulated sexual desire.
The drug produces the following positive effects on the body:
• elimination of symptoms and prevention of gynecomastia during steroid cycles – Pramipexole can be used during anabolic steroid cycles for the prevention or elimination of the already manifested negative symptoms of gynecomastia (feelings of discomfort, weight, itching in the nipples, their increase in size);
• stimulation of the natural secretion of growth hormone in the body;
• restoration of sexual activity, increased libido.
Pramipexole slightly increases the natural production of growth hormone. However, after using the drug, the concentration of Somatotropin in the body is guaranteed to be increased; this effect will be maintained for a couple of hours. The increase in growth hormone production results in muscle growth and stimulated burning of subcutaneous fat.

Pramipexole Possible Side Effects

Many athletes do not experience adverse reactions. Adverse reactions can rarely occur in the form of nausea as a common symptom of overdosing, vomiting, frequent headaches, reduced appetite, swelling of the limbs, muscle cramps, body weakness, hallucinations – such effects are extremely rare. Most often these side effects occur in the cases of overdosing and disappear along with a decrease in the daily dosage without the use of special drugs.

Pramipexole Administration and Dosage

Pramipexole is sold in tablets. The half-life of the active agent is 8-12 hours. Most commonly, the drug is sold packaged at 0.125/0.25/0.5/0.75 mg. It is recommended to start the cycle at minimal dosages so that the body can get gradually used to the drug. At the initial stage, 0.125 mg of the active agent are used two to three times a day. The dosage should be increased gradually, so that after a couple of weeks it reaches 0.75-1.5 mg daily. The duration of use of Pramipexole should not exceed several weeks; after the disappearance of gynecomastia symptoms users should stop taking the dopamine antagonist.
If Pramipexole is used to control the concentration of prolactin in the body, eliminate symptoms of gynecomastia and restore sexual function during an anabolic-androgenic drug cycle, then smaller dosages should be taken. For this, a dose of 0.25-0.5 mg of the active agent daily would be suitable. However, the cycle should start at minimal dosages – this ensures a gradual adaptation of the body to the action of the drug and minimizes the likelihood of manifesting adverse reactions.

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