Tesofensine by Apoxar Overview
Tesofensine by Apoxar is one of the very few companies in Canada and the US that manufacture pharmacy-grade Tesofensine.
This compound steps into the weight loss arena with a unique approach, targeting appetite control and metabolism. Tesofensine suppresses the reuptake of serotonin, norepinephrine, and dopamine in the brain, which not only curbs your cravings, but also dials down overall calorie intake.
Developed initially as a potential treatment for Alzheimer's and Parkinson's, its unexpected weight loss effects during clinical trials have shifted its primary research focus toward obesity management.
Apoxar Tesofensine Benefits
While it’s a relatively new peptide, there’s enough data to support its effectiveness in weight loss and general quality of life improvement:
Efficient Weight Loss
In the conducted Phase 2b trial, participants exhibited notable weight loss, up to 28.lbs across varying doses, all while maintaining a controlled diet and gradual increase in physical activity.
Appetite Suppression
Tesofensine’s appetite-suppressing power emanates from its ability to elevate levels of crucial neurotransmitters.
Improved Metabolic Indicators
During trials, Tesofensine has demonstrated improvements in insulin sensitivity and heightened glucose metabolism.
Fat Oxidation
Tesofensine can also amplify fat oxidation by approximately 15%, while diminishing protein oxidation. Practically, it means a significant reduction in fat tissue.
Tesofensine Side Effects
Despite tesofensine’s compelling benefits, it does bring along a suite of side effects to consider. Most users find tesofensine tolerable, with adverse effects in alignment with other weight-loss medications:
- Dry Mouth;
- Insomnia;
- Tachycardia;
- Constipation;
- Nausea;
- Diarrhea;
- High BP;
- Increased Heart Rate.
While the incidence of side effects is present, the wealth of safety data from over 20 clinical trials and roughly 1,600 patients provides a reassuring safety profile.
Tesofensine Dosage and Cycle
- Dosage: 0,25 mg to 1 mg;
- How long: up to 24 weeks.
There’s no general consensus on the doses, whether it should be closer to the lower or higher part of the 0,25-1 scale.
During the trials, dosage of 0,5 was just a little less effective than the one of 1 mg, therefore making it a generally accepted baseline, However, the effects are strictly individual, and if your personal response to Tesofensine brings more side effects at 0,5 mg dose, lowering it down to 0,25 is a reasonable strategy.