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Things that you must know about SARMS
15.12.2020

Things that you must know about SARMS

SARMs facts vs fiction: what they are, how they work, real side effects, suppression risks, and proven stacking protocols. Complete dosage tables and PCT guide.

Many athletes, bodybuilders, and those considering these compounds believe they already understand SARMs completely. However, several critical facts can surprise even experienced users. This guide covers what you actually need to know—not what forum threads claim.

Fact 1: SARMs Are Not Steroids

SARMs stands for "Selective Androgen Receptor Modulators." Their mechanism differs fundamentally from anabolic steroids. Rather than broadly activating androgen receptors throughout the entire body, SARMs selectively target receptors in specific tissues to produce a localized response.

Primary categories:

Category

Function

Examples

Bulking SARMs

Induce androgen receptor activation in muscle tissue

LGD-4033, RAD-140

Cutting SARMs

Promote fat loss while preserving muscle

Cardarine, Andarine

Recovery SARMs

Preserve tissue during caloric deficit

Ostarine

Cardarine - GW501516 (Fat Loss) 10mg/50tabs - NEO Sarms
Cardarine is the best SARM for weight loss and fat burning. It can be combined with any other SARM, peptide, or steroid agent for a more potent effect. Perfect anabolic agent for female bodybuilders. Usage: 10-20 mg/day Cycle
$90.00
5

Andarine - S4 (Muscle Mass) 10mg/50tabs - NEO Sarms
Andarine is not as potent as some other SARMs in terms of muscle gain, but it is a great solution to increase strength and endurance, burn fat, increase testosterone levels, improve bones' density and muscle definition & hardness. Less potent
$70.00
5

SARMs are not steroids, but stating they "might become a great alternative" implies equivalency. They are different compounds with different risk profiles—not simply "steroids lite."

Fact 2: You Have More Options Than You Think

SARMs are currently used by bodybuilders for multiple distinct purposes. Each compound has a specific application profile.

Goal

Primary Compounds

Secondary Options

Muscle mass

LGD-4033, RAD-140

YK-11

Fat loss

Cardarine, Andarine

Stenabolic

Muscle preservation

Ostarine

LGD-4033 (low dose)

Recomposition

LGD-4033, RAD-140

Ostarine

Vascularity

RAD-140

S-23

Cardio endurance

Cardarine

Stenabolic

Strength

RAD-140, LGD-4033

YK-11

Ostarine - MK2866 (Muscle Mass/Fat Loss) 10mg/50tabs - NEO Sarms
This SARM significantly improves muscle mass & physical performance, increases bone strength, and boosts collagen metabolism.  Will preserve muscle tissue and stimulate recovery & endurance Usage: 20-30 mg/day Cycle
$75.00
5

Fact 2: SARMs Do Not Lack Androgenic Effect—They Lack Androgenic Side Effects

SARMs are androgenic by definition—they are androgen receptor modulators. What they lack is the non-selective androgenic activity that causes acne, hair loss, and prostate stimulation.

The distinction matters. SARMs still bind androgen receptors. They simply do so preferentially in muscle and bone rather than scalp, skin, and prostate.

Fact 3: Stacking SARMs Is Not Only Possible—It's Optimal

Early speculation suggested that two SARMs would compete for the same androgen receptors, making stacking ineffective. However, practical experience and emerging research indicate that carefully selected SARM combinations can produce synergistic effects.

You should absolutely be selective about what you stack, not simply "not be afraid." Indiscriminate stacking increases suppression and hepatotoxicity without proportional benefit.

Table 1: Proven SARM Stacks With Dosage Guidelines

Beginner Lean Mass Stack

Compound

Dosage

Duration

Purpose

Ostarine (MK-2866)

20 mg/day

8 weeks

Foundational muscle preservation

Cardarine (GW-501516)

10 mg/day

8 weeks

Fat loss, endurance, lipid management

Ideal for first-time users. Ostarine provides measurable lean mass with mild suppression. Cardarine offsets the HDL reduction common with SARMs and improves training output. PCT is often unnecessary but bloodwork should confirm.

Intermediate Bulking Stack

Compound

Dosage

Duration

Purpose

LGD-4033

5–10 mg/day

8 weeks

Primary mass driver

RAD-140

10 mg/day

8 weeks

Strength, hardness, vascularity

Two potent SARMs combined. LGD provides wetter, faster mass; RAD adds density and dry strength. Suppression is significant. Bloodwork at week 4 recommended. PCT with Nolvadex (40/20/20/20) is strongly advised.

Advanced Cutting Stack

Compound

Dosage

Duration

Purpose

Ostarine

20 mg/day

8 weeks

Muscle preservation

Cardarine

20 mg/day

8 weeks

Fat oxidation, cardio

Andarine (S-4)

25 mg/day

6–8 weeks

Hardness, vascularity

Vision side effects from Andarine are dose-dependent. Start low. This stack preserves lean mass during aggressive deficits. Cardarine is not a SARM but complements the profile. PCT is usually not required but test levels should be verified post-cycle.

Testosterone Base + SARM Stack (Experienced Users Only)

Compound

Dosage

Duration

Notes

Testosterone Enanthate

200–300 mg/wk

10 weeks

Eliminates suppression sides

RAD-140

10–20 mg/day

8 weeks

Strength focus

LGD-4033

5 mg/day

8 weeks

Mass focus (optional)

Trenbolone Enanthate 200mg/ml - Apoxar
Trenbolone Enanthate is an excellent mass-building and muscle-strengthening agent. Usage: Inject 200-600 mg once a week Cycle Duration: 8-10 weeks for optimal results  Aromatization: No, but use with Caber, 0.5-1 mg E3D, 8-10
$120.00
5

This is not a SARM-only cycle. Testosterone base prevents lethargy and libido loss. Requires full PCT. Not for beginners. Not equivalent to "SARMs only."

Fact 4: Side Effects Are Not Fully Characterized—And That's the Problem

SARMs remain under clinical investigation. Their long-term safety profile in healthy athletes is not established. What we do know:

Side Effect

Frequency

Compounds Most Implicated

Testosterone suppression

Common

All, especially LGD, RAD, YK-11

HDL cholesterol reduction

Common

All

Liver enzyme elevation

Dose-dependent

Oral SARMs, especially YK-11

Vision disturbances

Moderate

Andarine (S-4)

Sleep disruption

Variable

RAD-140, YK-11

Fact 5: Suppression Is Not Optional

By week 4–5 of most SARM cycles, measurable testosterone suppression occurs. This happens because exogenous androgenic compounds signal the hypothalamus and pituitary to reduce endogenous gonadotropin production.

Factors influencing suppression severity:

  • Individual metabolic response
  • Actual compound content (counterfeit/underdosed products skew user reports)
  • Total androgenic load (stacking multiple compounds)
  • Cycle duration

Table 2: SARM Cycle Recovery Options

Suppression Level

Total Test (ng/dL)

Recommended Action

Mild

300–500

Monitor; natural recovery within 4 weeks

Moderate

200–300

Consider Nolvadex 20/20/10/10

Severe

<200

Nolvadex 40/20/20/20 + bloodwork

Prolonged

<200 after PCT

Medical consultation

Fact 6: Buying SARMs Is Unregulated—Act Accordingly

There is no FDA oversight for SARMs marketed as research chemicals or dietary supplements. Product labels frequently do not match contents. Independent laboratory testing has repeatedly found:

  • Products containing no active ingredient
  • Products containing different SARMs than labeled
  • Products adulterated with steroids
  • Products dosed incorrectly (both under and over)

There is no such thing as a "checked supplier" in an unregulated market. There are only suppliers who provide third-party analytical testing and those who do not. Require Certificates of Analysis from every purchase.

Conclusion

SARMs are not steroids, but they are not harmless. They are research compounds with legitimate therapeutic potential and real biological effects—including suppression, lipid impact, and unknown long-term consequences.

Stack intelligently. Dose conservatively. Test bloodwork. Verify your product.

If you cannot prove what is in your vial, you cannot predict what it will do.

  1. Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications
  2. Adverse effects and potential benefits among selective androgen receptor modulators users: a cross-sectional survey