Dianabol Profile (History, Chemical Structure, Characteristics)

History

Dianabol (aka Methandrostanalone) is an oral anabolic steroid originally synthesized by Dr. John Ziegler and released in the US in the early 60’s. Initially, methandrostenolone was used for faster recovery, burns treatment and even as a tonic for women. Soon it became a frequent practice to resort to the drug in bodybuilding for muscle mass gain, until it was banned by the FDA.

Chemical structure

Dianabol is an anabolic androgenic steroid, a derivative of testosterone. It contributes to muscle mass gain and decrease of fat deposits. Androgenic activity of the drug is somewhat lower than that one of testosterone. Regular use of the compound results in a positive nitrogen balance, stimulating the development of male secondary sexual characteristics — most importantly, muscle mass (1). 

Entering the cell nucleus, Dianabol methadrostenolone boosts synthesis of structural proteins, activating cell genetic apparatus, and increases tissue respiration, activating enzymes of tissue respiration chain. Activation of anabolic processes results in visible muscle mass gain and considerable decrease in body fat. The effect lasts for 14 hours.

Characteristics

Dianabol was born with a simgle purpose: give more anabolic effects with less androgenic ones. The experiment, initially started by the US national weightlifting team's physician, can be coinsidered more than successful: 

• Anabolic activity – 200% of testosterone;
• Androgenic activity – 50% of testosterone;
• Aromatization (conversion into estrogen) – Low;
• Mode of administration – oral;
• Activity – 6-8 hours;
• Detection time – up to 3 months.

Dianabol is proven to be effective (2) and it's been around for over half a century now. It rightfully bears the title of being a classic steroid. 

Dianabol Effects

Dbol is a clussic bulker: you grow, grow, and grow on it, and the effect starts almost immediately. It's not uncommon to see the results in the mirror by the end of the first week of the cycle, especially if you have low body fat. Compare it to Testosterone that will give the results in 3 or 4 weeks, and you get the main characteristic of Dianabol as a steroid: it's fast. 

• Dianabol is most effective in muscle mass gain due to the activation of glycogenolysis synthesis;
• Improved performance;
• Better appetite;
• Slight fat-burning effect;
• Strengthened bones;

Methandrostenolone has relatively weak androgenic activity (50% of that one of testosterone). Most often side effects are caused by overdosing and abuse (more than 50mg of Danabol per day).

Methan Dosage and Results

Practice shows that a 6-week cycle of methandrostenolone with a dose of 30mg per day can increase the muscle mass by 15-20lbs with the subsequent loss of 4-8lbs (so called rollback). Provided that the administered course is correct, the rollback  can be minimized. 

Practical Cycle Guide and FAQ

Dianabol shines best as a jump-start for other, slower steroids. If you start Testosterone Enanthate and Dianabol at the same time, Dbol will give all its effects by the moment Test E will start improving your muscle mass in 3 or 4 weeks.

Start Dianabol early into the cycle and drop it half-way through: this way, you'll get your gains faster, with less side effects from 2 compounds in simultaneous use.

Can You Try Dianabol Solo Cycle?

It's a myth: nobody should ever cycle Dianabol alone. It's highly suppressive and it does NOT make up for the loss of your natural testosterone. In other words, you get shut down: no Testosterone at all, with a variety of estrogenic side effects. 

Instead — run it with a subsequent testosterone base. About 150mg of Testosterone, slightly above the TRT level, will compensate Dbol's suppressive effects and let you enjoy your gains with no harsh side effects. 

Best Dianabol Bulking Protocol

The following cycle of Dianabol methandrostenolone works best for men over 21 for the muscle mass gain in the absence of contraindications (high blood pressure, heart diseases, prostate hypertrophy, liver disorders etc.).

Do not exceed the recommended daily dose of 30 mg. It should be divided into 2-3 intakes (e.g. 20mg in the morning and 10mg in the afternoon). Methane (methandienone) is toxic to the liver, that’s way the drug should better be taken after meals.

1. The cycle of Dianabol methandrostenolone starts with 10 mg and in 2-3 days the dose can be gradually increased up to 20-30mg per day (to check the tolerability). The cycle usually lasts for 6 weeks.
2. In a week time it is recommended to include aromatase inhibitors into the course. For example, you can take 0.5mg of Anastrozole every third day. It will suppress estrogen conversion and what is more important – eliminate the problems of fluid retention and edema.
3. In 2-3 days after the course PCT should take place: 20mg of tamoxifen for 2-4 weeks. During the last week the dosage is gradually reduced until the drug withdrawal.

Blood pressure needs monitoring. In case of increased blood pressure, you should reduce the dosage or start taking hypotensive drugs (e.g. 5 mg of Enalapril).

Each course can be followed by 3-4 weeks of testosterone booster cycles for the faster recovery of testosterone secretion in the body and the prevention of the rollback phenomenon.

To achieve the best possible results and to minimize the muscle mass loss after the course it is recommended to take supplements and to stick to the mass gain diet.

Best Dianabol Stacks

Taking into account the high frequency of methandrostenolone side effects and small range of positive effects, many authors recommend taking this drug in combination with other anabolic steroids. The dosage of methandrostenolone can vary between 10-30mg. Combined cycles increase effectiveness and decrease side effects frequency due to different pharmacodynamics of drugs.

For muscle mass gain Dianabol methandrostenolone should be combined with:

• Nandrolone
• Testosterone
• Sustanon
• Trenbolone
• Primobolan

Mind that Dianabol methandrostenolone administration must be always accompanied by at least therapeutic doses of testosterone. Remember that every combination presupposes strictly defined doses of both drugs and a special mode of administration. 

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References

1. Effect of short-term treatment with an anabolic steroid (methandienone) and dehydroepiandrosterone sulphate on plasma hormones, red cell volume and 2,3-diphosphoglycerate in athletes — https://www.tandfonline.com/doi/abs/10.3109/00365517709100649
2. Effects of methandienone on the performance and body composition of men undergoing athletic training — https://pubmed.ncbi.nlm.nih.gov/7018798/