Novo-pharm Femara – Letrozole General Description
Letrozole is one of the most active inhibitors of aromatase which suppresses the blood concentration of estrogens. The drug, however, is not part of the steroid drug group. It's very common in medicine and sports.
The medication is used in treatment of women with breast cancer following menopause. The basic principle of effect of the drug has made it popular in sports – aromatase inhibitors are used by athletes because negative side effects can occur during the administration of laboratory-synthesized testosterone in the form of anabolic steroids in heavy aromatization cases.
Estradiol serves as the primary female sex hormone and can be developed by testicles in small concentrations. Using hormonal anabolic drugs can lead to hormonal imbalances and increased body estradiol secretion. Letrozole blocks aromatase enzymes that stimulate the development of estradiol.
Novo-pharm Femara – Letrozole Benefits
Scientific studies have shown that letrozole lowers the levels of estrogen by 97 percent, suggesting its high efficiency. Using the drug at prescribed dosages results in a 76-79 percent reduction in estradiol concentration, which is also a good result. Low estrogen levels in the body reduce adverse reactions caused by cycles of steroids. In sports, the use of Letrozole stimulates the production of follicle-stimulating and luteinizing hormones which affect the natural testosterone production. The aromatase inhibitor stimulates spermatogenesis as well, which helps restore sexual health after a steroid cycle.
The drug’s usage leads to the following positive effects:
• suppression of gynecomastia onset at the initial stage of the steroid cycle;
• preservation of accumulated muscle mass, suppression of catabolic processes that break down muscle tissue;
• elimination of estrogen-related adverse reactions (acne, female pattern fat deposits, swelling).
It is advised to use Novo-pharm Letrozole during potent drug cycles of anabolic-androgenic steroids. To eliminate subcutaneous fat and achieve better muscle definition, the aromatase inhibitor can be used as part of a cutting cycle. Novo-pharm Letrozole promotes the reduction of body fat while, with the addition of vascularity, muscles maintain their shape. The medication should be used with a low-calorie diet. Letrozole is the group's most effective drug relative to other aromatase inhibitors (Anastrozole, Exemestane).
Novo-pharm Femara – Letrozole Possible Side Effects
Estrogens are not a negative in the male body on their own – moderate female hormone concentration is beneficial in achieving the best sporting results as hormones increase androgen receptor susceptibility. Total estrogen development inhibition adversely affects health.
Proper drug use does not result in unwanted reactions. Otherwise, the issues concerning the physical well-being of athletes may include frequent headaches, pain in the joints, excessive mobility of the joints, fever, fatigue, bouts of nausea, high blood pressure, hair loss, dizziness.
These symptoms only occur if patients exceed the recommended dosage of the medication and fail to comply with the required cycle period.
Novo-pharm Femara – Letrozole Administration and Dosage
One of Letrozole's main advantages is its excellent tolerance by the body, so almost any competitor can use it in sports. Athletes who have been diagnosed with severe liver dysfunction should be given special treatment. In that case, before using an aromatase blocker, it is advised to consult a specialist. During a cycle, people with specific intolerances to the active agent need to be vigilant and monitor allergic reactions. The medication is also not recommended for female athletes because of the risk of hormonal imbalances.
During an anabolic-androgenic steroid cycle, Novo-pharm Letrozole should be used to avoid side effects and to counteract the signs that already occur. The drug is used once every two days at 0.5 mg of the active agent (1/5 of a tablet) as a preventive measure. When there have already been signs of aromatization, then 2.5 mg of the aromatase blocker (a whole tablet) should be taken daily until the symptoms disappear, after which patients should use preventive doses. Letrozole doses can vary depending on the athlete's health – if the erectile function or depression is affected, the dose may be decreased.
Checking for estradiol levels about 10 days after the end of the short ester drug cycle is important. When a steroid with intermittent activity is used during the cycle, the tests are done 3-4 weeks after the cycle begins with the application of the drug's therapeutic doses. The tests must be carried out again after 10 days.
Novo-pharm Femara – Letrozole Combined Cycles
Letrozole is used for one week (with possible extension to 13 days) at 2.5 mg daily during post-cycle therapy. Therefore, the daily dose is decreased to 0.5 mg between days 14-21. During post-cycle therapy, normal hormonal levels are restored, muscle mass is preserved, signs of regression to the female form are prevented in male users, preventive measures against oligospermia and testicular atrophy are taken, and the risks of steroid-related adverse reactions are reduced.
During a steroid cycle, it is recommended to use Letrozole with drugs that are prone to high aromatization, e.g. different testosterone esters, methandrostenolone and others. Athletes may determine the time to begin the use of the aromatase inhibitor subjectively, when the first aromatization symptoms (swelling of the nipples, redness, itching) first occur while using the correct dosage. It is safer to use antiestrogens for PCT because they show more effective results for restoring the body after a cycle of steroids.
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