Retatrutide, a multireceptor agonist of the incretins, is a glucagon-like peptide-1 receptor (GLP1R) agonist, a glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist, and a glucagon receptor agonist .These receptors are involved in controlling hunger and satiety, allowing patients to feel satiated longer after a meal. Helps to lower blood sugar levels and reduce body weight.